Hi!

I'm Rik Deitsch, the chief scientific officer of Avini Health, and I'm here to talk about Plus Relief. Plus Relief is an all-natural homeopathic analgesic pain reliever and anti-inflammatory product. And it works because of cobra venom. Yep, cobra venom from Asian cobras.

See, the venom of the cobra has these peptides, small proteins that are neurotoxic which means they bind to nerves in the body and because of that they have all sorts of physiologic effect. Well, let me ask you that question. Is there any doubt in your mind that when a cobra bites you it has a physiologic effect? Of course not. But if you take a 10,000 times dilution that cobra venom instead of being deadly, instead of being toxic, it's actually beneficial and therapeutic.

You see, these peptides bind to receptors in the nerves that modulate the receptors, particularly a receptor called the Alpha-7 subtype of this nicotine acetylcholine receptor which is found in the central nervous system and on this white blood cells. So it modifies the pain signal, turns it down and it blocks inflammation. It does it very, very efficiently.

Now, the way that works is big signals like pain become little tiny signals because that binding on and off again on that receptor. And additionally, white blood cells which cause inflammation get modulated modified so they cannot cause the inflammatory cascade. It does it in a safe and effective manner.

The way the peptide binds to the receptor is really interesting too because it's not a perfect fit. Every time that peptide binds, the receptor the receptor has to change shape. It's a concept known as induced fit.

As you use the product, over time the receptor gets more and more used to that conformational shift and instead of growing resistant to the product your body grows sensitive to it. So over time you need less and less to get the same benefit which is the exact opposite of every other pain therapy on the market.

The Plus Relief is available as an oral spray and a topical gel. The oral spray you just spray in your mouth, it goes through the buckle, mucosa in the mouth and into the digestive tract and gets absorbed and it's good for pain all over the body. So this is large areas of pain, head and neck pain, back pain. If you have arthritis it's a great product to use because it goes everywhere.

Now it does take up to five days to maximize so you want to keep using it and give it a chance. The studies we've done with the Plus Relief actually show that it gets into the brain and affects the paraphuscular nucleus where pain is processed. So it's so far upstream it should work in all forms of pain, even internal visceral pain. So it should work pretty much for everyone because it's a universal mechanism of action.

Now, the topical gel is available as an easy squeeze, a roll on and our eight ounce pump. It's all the same product. It's just different methods of delivering it. Now, the topical gel works specifically wherever you put it. You can rub it anywhere. It's really great for areas where there aren't a lot of fat or muscle. So that's your hands, your wrists, your elbows, your knees, your ankles. It's especially good in things like carpal tunnel syndrome, TMJ. It goes right in and right away. Affects pain within 20 minutes, lasts about 4 to 6 hours.

And as I said, the more you use over time, the less you need. So it's a great way to deal with pain and inflammation in a safe, effective way, without side effect. It's non-opiate, non-narcotic, non-interactive. It doesn't cause any of the side effects we normally associate with pain medications.

And it's like I said, safe, effective, all natural homeopathic pain relief. And the greatest thing about the topical gels is there's no heat, no cold, no smell, just pain relief from Asian Cobra venom. And it's only available through Avini Health.